Carcinogenesis, Teratogenesis & Mutagenesis ›› 1998, Vol. 10 ›› Issue (4): 218-223.doi: 10.3969/j.issn.1004-616x.1998.04.006

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MUTAGENIC ANALYSIS ON ORGANIC EXTRACTS OF AEROSOL SAMPLES IN NEW CITY REGION OF KOWLOON H. K.

Mo Ziyao1 ,Xiao Binquan1 ,Joseph K. Kwan2 , Samuel CT Yu2 , Ming Fang2   

  1. 1 The Munici pal Heal th and A ntiepidemic S tation of Guangz hou , Guangz hou , P. R . China 510080 , 2 The Hong Kong University of Science and Technology , H. K.
  • Received:1900-01-01 Revised:1900-01-01 Online:1998-07-30 Published:1998-07-30

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Abstract: The mutagenicity of methylene chloride ext racrs of aerosol samples f rom 1995 - 96 in new city region of Kowloon was studied with st rain TA98 and TA100 in Ames Test . It was found that the ext ract samples contained both f rameshift mutagens and base2pair substitute ones. The lowest concent rations produced positive reaction in given monthes were just 5μg/ plate or 2M3/plate , which meant the level of some mutagens in ambient air was higher. The results were also suggested that there were some other mutagens instead of PAH which played an important role in the classical test of air pollution. The mutagenicity of the ext ract s showed obviously a change with the seasons and geographical features(higher in winter and lower in summer) ,as well as a correlation with the change of that in the close region of South China.

Key words: air pollution, ext ract, mutagenicity, Ames test