癌变·畸变·突变 ›› 1999, Vol. 11 ›› Issue (3): 131-134.doi: 10.3969/j.issn.1004-616x.1999.03.009

• 论著 • 上一篇    下一篇

天宝肿宁散对五种肿瘤细胞抑制作用的实验研究

周 俊1  张月明2  殷学军1  闫 浩2  孙健玲2   

  1. 1兰州军区乌鲁木齐总医院临床医学研究所 乌鲁木齐 830000  2新疆医学院预防医学系 乌鲁木齐 830054
  • 收稿日期:1998-09-29 修回日期:1999-03-11 出版日期:1999-05-30 发布日期:1999-05-30

THE EXPERIMENTAL STUDY ON THE INHIBITION EFFECTS AT FIVE CANCER CELLS OF“TIAO BAO ZHONG NING SAN”

Zhou J un1 , Zhang Yueming2 , Yin Xuejun1 , et al   

  1. 1 Instit ute of Clinical Medicine , Urumqi General Hospital of L anz hou Com mand , PL A , Urumqi 830000  2 XinJiang Medical College , Urumqi  830054
  • Received:1998-09-29 Revised:1999-03-11 Online:1999-05-30 Published:1999-05-30

摘要: 采用体外细胞培养法观察“天宝肿宁散”方剂对小鼠成纤维细胞(3T3) 和人膀胱癌细胞( EJ ) 、人喉癌细胞(Hep - 2) 、人低分化粘液腺胃癌细胞(MGC - 803) 、人肝癌细胞(Q3) 以及人肺癌细胞(Spc - A - 1) 等肿瘤细胞的细胞存活量的影响,并以此评价该方剂对各株细胞生长的抑制作用,结果显示该方剂在体外能显著抑制肿瘤细胞生长,并呈一定剂量效应关系,而对3T3细胞未呈现出抑制作用。说明该方剂具有作为抗癌药开发利用的价值。

关键词: 中药方剂, 肿瘤细胞, 抑制作用

Abstract: To evaluate the inhibition effect s on cancer cells of Chinese herbs“Tian Bao Zhong Ning San”with cultured cells in vivo such as fibroblast lines of mouse(3T3) , bladder carcinoma cell lines( EJ ) , throat carcinoma cell lines(Hep - 2) , stomach carcinoma cell lines(MGC - 803) , hepatic carcinoma cell lines(Q3) and lung carcinoma cell lines(Spc - A - 1) . The result s showed that the alcohol ext ract s of“Tian Bao Zhong Ning San”had significant inhibition on the growth of cancer cells. And there was a dose2effect relationship between them. But this alcohol ext ract s had no inhibition on 3T3. So the result s proved that this Chinese herbs could be used as a antitumor drug.

Key words: Chinese herbs, Cancer cells, Inhibition effect, in vivo