兰州市不同交通路口汽车尾气污染及颗粒提取物的DNA 损伤作用研究

doi:10.3969/j.issn.1004-616x.1998.03.007

癌变·畸变·突变 ›› 1998, Vol. 10 ›› Issue (3): 152-155.doi: 10.3969/j.issn.1004-616x.1998.03.007

兰州市不同交通路口汽车尾气污染及颗粒提取物的DNA 损伤作用研究

闫春生1 　赵晓红2

1兰州医学院　预防医学系　兰州　730000 　2兰州大学　生物系　兰州　730000

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1998-05-30 发布日期:1998-05-30

AUTOMOBILE EMISSION POLLUTION AND DNA DAMAGE EFFECT OF PARTICLE EXTRACTS IN DIFFERENT STREETS

Yan chunsheng ; Zhao xiaohong2

Dept . of the Preventive Medicine , L anz hou Medicine College , L anz hou 　730000 2.Dept . of the Biology , Lanzhou University , Lanzhou 　73000

Received:1900-01-01 Revised:1900-01-01 Online:1998-05-30 Published:1998-05-30

摘要/Abstract

摘要： 本文对兰州市盘旋路、民主西路和南关什字三种类型的交通路口的汽车尾气污染物进行监测,并采用体外淋巴细胞姐妹染色单体交换试验( SCE) 检测各点颗粒提取物的DNA 损伤作用。结果表明,不同路口TSP、NOx、CH、SO2 、CO 和Pb 的浓度与车流强度、道路状况及车辆行驶状况有明显关系,各点的颗粒提取物与对照点比较,均能引起姐妹染色单体交换频率升高,且具有显著统计学差异,并有一定的剂量———反应关系。以民主西路的增高最明显,其次为盘旋路,而南关什字最低。说明本市汽车尾气污染十分严重,并具有潜在的致癌危险性。

关键词: 汽车尾气, DNA 损伤作用, SCE

Abstract: In this paper , pollutions of automobile emission in three st reet s were monitored and DNA damage effect s of particle ext ract s were studied with sister chromatid exchangs (SCE) test in peripheral blood lymphocytes. The result demonst rated that concent rations of TSP , NOx ,SO2 , CO and Pb were interrelated with the density of motors and the situation of roads and driving status. The f requencies of SCE of particles at different st reet were increased markedly ( P < 0.05) with dose2response relationship. Min Zhu Xi Lu was the highest , then Pan Xuan Lu and Nan Guan Shizi the lowest . It also indicates that automobile emisssion pollution of this city has been very serious and may have potent carcinogen.

Key words: Automobile emission, Particle ext ract s, SCE, DNA damage

闫春生　赵晓红. 兰州市不同交通路口汽车尾气污染及颗粒提取物的DNA 损伤作用研究[J]. 癌变·畸变·突变, 1998, 10(3): 152-155.

Yan chunsheng , Zhao xiaohong. AUTOMOBILE EMISSION POLLUTION AND DNA DAMAGE EFFECT OF PARTICLE EXTRACTS IN DIFFERENT STREETS[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 1998, 10(3): 152-155.

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兰州市不同交通路口汽车尾气污染及颗粒提取物的DNA 损伤作用研究

AUTOMOBILE EMISSION POLLUTION AND DNA DAMAGE EFFECT OF PARTICLE EXTRACTS IN DIFFERENT STREETS

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