癌变·畸变·突变 ›› 1998, Vol. 10 ›› Issue (4): 218-223.doi: 10.3969/j.issn.1004-616x.1998.04.006

• 论著 • 上一篇    下一篇

香港九龙新城区大气有机提取物致诱变性分析

莫自耀1 　肖斌权1 　关继祖2 　俞宗岱2 　方　明2   

  1. 1广州市卫生防疫站　广州　510080 　2 香港科技大学
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1998-07-30 发布日期:1998-07-30

MUTAGENIC ANALYSIS ON ORGANIC EXTRACTS OF AEROSOL SAMPLES IN NEW CITY REGION OF KOWLOON H. K.

Mo Ziyao1 ,Xiao Binquan1 ,Joseph K. Kwan2 , Samuel CT Yu2 , Ming Fang2   

  1. 1 The Munici pal Heal th and A ntiepidemic S tation of Guangz hou , Guangz hou , P. R . China 510080 , 2 The Hong Kong University of Science and Technology , H. K.
  • Received:1900-01-01 Revised:1900-01-01 Online:1998-07-30 Published:1998-07-30

PDF

2517

摘要： 我们在1995 —1996 年度用Ames 试验方法,对香港九龙新城区大气有机提取物进行致诱变性分析。结果发现,样品抽提物中既含有移码型突变物也含有置换型突变物,所产生诱变阳性结果的剂量在一些月份仅为2M3/ 皿或5μg/ 皿,表明有关的污染物水平含量较高,但传统研究中的PAH 作用则似乎并不明显,提示有另一类突变物存在。大气提取物的诱变性表现出明显的季节性变化和地域特征,冬季较高而夏季较低并与相邻地区的变化有相关性。

关键词: 大气污染, 提取物, 致诱变性, Ames 试验

Abstract: The mutagenicity of methylene chloride ext racrs of aerosol samples f rom 1995 - 96 in new city region of Kowloon was studied with st rain TA98 and TA100 in Ames Test . It was found that the ext ract samples contained both f rameshift mutagens and base2pair substitute ones. The lowest concent rations produced positive reaction in given monthes were just 5μg/ plate or 2M3/plate , which meant the level of some mutagens in ambient air was higher. The results were also suggested that there were some other mutagens instead of PAH which played an important role in the classical test of air pollution. The mutagenicity of the ext ract s showed obviously a change with the seasons and geographical features(higher in winter and lower in summer) ,as well as a correlation with the change of that in the close region of South China.

Key words: air pollution, ext ract, mutagenicity, Ames test

版权所有 ©2019 《癌变·畸变·突变》编辑部 E-mail： office@egh.net.cn
本系统由北京玛格泰克科技发展有限公司设计开发 技术支持：support@magtech.com.cn
粤ICP备 10216025号