癌变·畸变·突变 ›› 1998, Vol. 10 ›› Issue (4): 230-232.doi: 10.3969/j.issn.1004-616x.1998.04.009

• 论著 • 上一篇    下一篇

维生素A 和亚硒酸钠对菜油烟冷凝物致小鼠毒性作用的影响

周纯先 王帮霞 肖 棣   

  1. 蚌埠医学院卫生学教研室 蚌埠 233003
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1998-07-30 发布日期:1998-07-30

EFFECT OF VITAMIN A AND SODIUM SELENITE ON RAPESEED OIL VAPOR CONDENSATE TOXICITY IN MICE

Zhou Chunxian , Wang Bangxia , Xiao Di   

  1. Department of Public Heal th , Bengbu Medical College , Bengbu  233003
  • Received:1900-01-01 Revised:1900-01-01 Online:1998-07-30 Published:1998-07-30

摘要: 本文报道了维生素A 和亚硒酸钠对菜油烟冷凝物致小鼠毒性作用的影响。结果表明: ①菜油烟冷凝物组小鼠的体重明显低于补充维生素A 组和亚硒酸钠组( P < 0. 01) ; ②菜油烟冷凝物组小鼠的心脏器系数高于补充维生素A 和亚硒酸钠组( P < 0. 05) ; ③补充维生素A 和亚硒酸钠后,可显著地降低菜油烟冷凝物所致的小鼠微核率和精子畸形率( P < 0. 001 和P < 0. 01) ,而单纯菜油组则无致小鼠微核率和精子畸形率升高的作用( > 0. 05) 。

关键词: 维生素A, 亚硒酸钠, 菜油烟冷凝物, 小鼠, 毒性作用

Abstract: The effect of vitamin A(Vit A) and sodium selenite (Na2SeO3) on rapeseed oil vapor condensate toxicity was studied in mice. The result sare : ①The body weight of rapeseed oil vapor condensate group mice was significantly lower than that of addition Vit A group and Na2SeO3 group ( P < 0. 01) ; ②The heart organ index of rapeseed oil vapor condensate group mice was higher than that of supplyment Vit A group and Na2SeO3 group ( P < 0. 05) ; and ③The rate ofmicronuclei and of sperm aberrations of rapeseed oil vapor condensate group were obviously higher than that of plus Vit A group and Na2SeO3 group ( P < 0. 001 and P < 0. 01) , but rapeseed oil group mice was didn’t ( P > 0. 05) .

Key words: Vitamin A, Sodium selenite, Rapeseed oil vapor condensate, Mice, Toxicity effect s