癌变·畸变·突变 ›› 1999, Vol. 11 ›› Issue (5): 224-226.doi: 10.3969/j.issn.1004-616x.1999.05.005

• 论著 • 上一篇    下一篇

氯化消毒对自来水致突变性影响研究

张淑琪 王根凤 王占生   

  1. 清华大学环境科学与工程系 北京 100084
  • 收稿日期:1999-04-03 修回日期:1999-06-25 出版日期:1999-09-30 发布日期:1999-09-30

THE GENETIC TOXICOLOGIC EFFECTOF CHLORINATINGDISINFECTION ON DRINKINGWATER

Zhang Shuqi , Wang Genfeng , Wang Zhansheng   

  1. Department of Envi ronmental Science and Engineering , Tsinghua University , Beijing  100084
  • Received:1999-04-03 Revised:1999-06-25 Online:1999-09-30 Published:1999-09-30

摘要: 本文通过鼠伤寒沙门氏菌致突变试验(Ames Test) ,分析常用氯化消毒方法对饮用水遗传毒性的影响。水样采自某单位自备水源。试验结果表明,未氯化自来水有机提取物致突变反应阴性,加氯自来水样诱发沙门氏菌致突变率升高;在一定范围内,随氯浓度增加,不会显著增加水样的致突变性。同时检测加氯后中和水样的致突变性,加中和剂处理后水样致突变性降低。提示加氯消毒水样致突变性可以通过水处理工艺加以改进,为饮水氯化消毒的致突变研究及其防治提供毒理学依据。

关键词: 致突变性, Ames 试验, 氯化, 饮用水

Abstract: By means of Ames test , the genetic toxicology of chlorination on drinking eater is evaluated. The result showed that the mutagenecity of water increased in all samples t reated with chlorine , while mutagenic potential was negative in source water samples not t reated with chorine. By adding Na2S2O3 to chlorinated water samples , there had less mutagenic activity. The antimutagenic potentials of Na2S2O3 in the chlorine water was dose dependent , the higher the mutagenicity of chlorined water , the better the beneficial effect of nasal. These indicated that the mutagenecity in chlorined water can be reduced by water t reatment process.

Key words: mutagenicity, Ames test, chlorine, drinking water