关键词: Ag-NORs, T淋巴细胞, I.S％, KL型免疫分析系统

Abstract: BACKGROUND ＆ ATM: To provide a scientific method of evaluating the tumor patients' prognosis and the assistant diagnosis by analyzing patients' immunocompetence by quantitating the Ag-NORs in periopheral blood T lymphocyte. MATERIAL AND METHODS:Quantitive analysis of the Ag-NORs in periopheral blood T lymphocyte was performed at the gene transcription level with the KL-immunological analysis system, using the ratio between the surface areas of silver-dyed and the nucleus(I.S ％)as the index to reflects the rDNA transcription activity.RESULTS:Significant difference was found between the values of the I.S％ in malignant tumor patients and in health persons. The values of the I.S％ in tumor patients were much lower than that of the health persons.No statistical difference was found between the values of the I.S％ in all kinds of malignant tumor patients that we studied. CONCLUSION:Testing Ag-NORs in periopheral blood T lymphocyte has the important significance to distinguish the malignant tumor patients from the health persons,but it can't distinguish between all kinds of malignant tumors.

Key words: Ag-NORs, T lymphocyte, I.S％, KL-immunological analysis system