胃癌干细胞在胃癌靶向治疗中的研究进展

doi:10.3969/j.issn.1004-616x.2018.06.015

摘要/Abstract

摘要： 越来越多的证据表明，胃癌干细胞参与胃癌的侵袭、转移和治疗耐药性的进程。随着识别、分离和验证干细胞技术的不断完善，已经初步阐明了胃癌干细胞特异性标记物和相关信号通路，这可能为基于根除胃癌干细胞为目标的胃癌治疗提供了新思路。本文就胃癌干细胞的来源及分离、鉴定特性，针对胃癌干细胞表面标记、自我更新相关信号通路及端粒酶活性的靶向治疗作一综述。

关键词: 胃癌, 肿瘤干细胞, 靶向治疗, 肿瘤标志物, 上皮-间充质转化

中图分类号:

R735.2

崔宏伟, 苏秀兰. 胃癌干细胞在胃癌靶向治疗中的研究进展[J]. 癌变·畸变·突变, 2018, 30(6): 490-493.

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胃癌干细胞在胃癌靶向治疗中的研究进展

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