2,2′,4,4′-四溴联苯醚毒性的研究进展

doi:10.3969/j.issn.1004-616x.2022.05.011

摘要/Abstract

摘要： 2,2',4,4'-四溴联苯醚(BDE-47)是最常见的溴代阻燃剂之一，广泛添加于电子产品、建筑材料、家具等各种产品中。虽然，近年来BDE-47的使用在一定程度上受到限制，但是由于其难降解、半衰期长等特点，BDE-47广泛存在于水、土壤和空气等多种环境介质中。BDE-47在环境中具有生物累积和放大效应，能够通过呼吸道、消化道和皮肤等途径进入体内。已有研究表明，在野生动物和人体内均能检测出较高水平的 BDE-47，并能造成多种毒效应。本文归纳了 BDE-47在环境及人群中的暴露情况，并总结了 BDE-47毒效应的最新研究进展，重点介绍了 BDE-47的神经、生殖发育、内分泌、肝脏和免疫毒性及其毒作用机制，旨在提高民众对BDE-47毒效应的认识与重视，并为深入研究BDE-47毒性提供线索。

关键词: 四溴联苯醚, 环境污染物, 阻燃剂, 毒效应, BDE-47

中图分类号:

R994.6

邹天乐, 刘筱靖, 林倩, 李沙沙, 杨一, 林桂淼. 2,2′,4,4′-四溴联苯醚毒性的研究进展[J]. 癌变·畸变·突变, 2022, 34(5): 395-399.

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