癌变·畸变·突变 ›› 2004, Vol. 16 ›› Issue (2): 104-106.doi: 10.3969/j.issn.1004-616x.2004.02.012

• 研究简报 • 上一篇    下一篇

葛根在减少烟焦油诱发小鼠骨髓细胞微核的研究

曹 能;敖新宇;唐继红;田文华;牟智蜀   

  1. 云南师范大学生命科学学院,云南 昆明 650092
  • 收稿日期:2003-10-10 修回日期:2003-11-20 出版日期:2004-03-30 发布日期:2004-03-30
  • 通讯作者: 曹 能

The Research of the Pueraria Edulia Pamp in Reducing the Mouse Bone Marrow Cell's Micronucleus Caused by Tobacco Tar

CAO Neng,AO Xin-yu,TANG Ji-hong,et al   

  1. College of Life Science,Yunnan Normal University,kunming 650092, China
  • Received:2003-10-10 Revised:2003-11-20 Online:2004-03-30 Published:2004-03-30
  • Contact: CAO Neng

摘要: 背景与目的: 本实验以出现微核的小鼠骨髓嗜多染红细胞频率为指标,检测葛根减少烟焦油毒害的作用。 材料与方法: 将小鼠分组用各受试物处理,常规法制片观察,统计学方法分析各组小鼠微核细胞率。结果: 在注射等量烟焦油的小鼠中,服用葛根组小鼠中微核细胞率明显低于对非服用组小鼠。结论: 葛根在减少香烟毒害方面有积极作用,提示中药葛根应用于香烟减毒领域有重要意义。

关键词: 葛根, 烟焦油, 小鼠骨髓嗜多染红细胞, 微核

Abstract: BACKGROUND & AIM:In this experiment we used the rate of micronucleus in mouse bone marrow eryhrocyte as norm ,to test the pueraria edulia pamp's effect for reducing the damage caused by tobacco tar. MATERIAL AND METHODS: Dividing the mice in to different groups dealing with different reagents.Use the normal method to make the specimens and observe,Analyzing the rats of micronucleus cells in different groups of mouse by statistics. RESULTS: The rate of micronucleus cells in mouse of the group that was fed with pueraria edulia pamp was less than that of the control group. CONCLUSION:There are positive effect of the pueraria edulia pamp in reducing the damage caused by tobacco.

Key words: Pueraria edulia Pamp, tobacco tar, mouse bone marrow eryhrocyte, micronucleus