噻磺隆原药的致突变性研究

doi:10.3969/j.issn.1004-616x.2003.03.017

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2003, Vol. 15 ›› Issue (3): 180-182.doi: 10.3969/j.issn.1004-616x.2003.03.017

Previous Articles Next Articles

STUDY ON MUTAGENICITY OF THIFENSULFURON

FENG Xue-qing, YE Lin, WANG Wei,et al

Anhui Institute of Occupational Health, Hefei 230022,China

Received:2002-12-30 Revised:2003-02-06 Online:2003-07-30 Published:2003-07-30
Contact: FENG Xue-qing

Abstract

Abstract: Purpose:To explore potential mutagenicity of thifensulfuron. Methods: The potential mutagenicity of thifensulfuron was studied by Ames test, micronucleus test of polychromatic erythrocytes in bone marrow and chromosomal aberration test of spermatocytes in mice to provide the data for its safety. Results: No increase in the number of revertant colonies was found in the Ames test in all dosage groups. The results were also negative in the chromosomal aberration test of spermatocytes in mice and in the micronucleus test at doses from 1 000 to 5 000 mg/kg. Conclusion: The mutagenicity of thifensalfuron was not showed in this study.

Key words: thifensulfuron, Ames test, chromosome aberration, micronucleus, mutagenesis.

FENG Xue-qing, YE Lin, WANG Wei, et al. STUDY ON MUTAGENICITY OF THIFENSULFURON[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2003, 15(3): 180-182.

[1]	SHI Wenjing, ZHANG Jiqianzhu, ZHU Jiangbo, ZHANG Xiaofang, WANG Ruina, DAI Xiaoyu, REN Lijun, TIAN Yijun. Evaluation of genotoxicity of diphenhydramine hydrochloride and caffeine compound [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2022, 34(2): 149-153,157.
[2]	DU Xiuming, HONG Liling, XU Lingzhi, ZHOU Qingyun. In vitro chromosome aberration evaluation of anatase titanium dioxide nanoparticles [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2022, 34(1): 67-71.
[3]	CAI Qi, GAO Deyu, SHI Jianfeng, YU Hao, HAN Yan, YANG Liu, ZHAO Lei, WANG Zhaoxu. Potential use of tree shrew as an animal model for the micronucleus test [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(5): 370-374,382.
[4]	LU Xue, TIAN Xuelei, ZHAO Hua, CAI Tianjing, TIAN Mei, LIU Qingjie. Use of the micronucleus assay to estimate partial radiation exposure dose in vitro [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(3): 193-196.
[5]	ZHAO Hua, LU Xue, CAI Tianjing, TIAN Mei, LIU Qingjie. Effects of age and gender on formation of nucleoplasmic bridges in peripheral blood lymphocytes [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(1): 48-52.
[6]	CAO Yiyi, LIU Weiying, YOU Xinyue, XI Jing, Chen Ruixue, ZHANG Xinyu, LUAN Yang. In vitro genotoxicity evaluation of BDE-3, BDE-47 and BDE-209 [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(1): 15-20,28.
[7]	ZHOU Su, LI Rui, ZHU Hongyan, ZHANG Zhichao, FANG Jing, TANG Liming. An optical density method for determining bacterial concentrations in the Salmonella typhimurium reverse mutation assay [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(1): 62-66.
[8]	WANG Quankai, XIE Guangyun, MA Shunpeng, GUO Haoran, WUHAN Baolier, SONG Jiayang, XU Jianning. Genotoxicity evaluation of glycidyl methacrylate [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(6): 479-482.
[9]	ZHENG Kai, WANG Bingyu, XU Xinyun, GENG Hong, HUANG Haiyan, LIU Wei, LONG Dingxin. Mutagenicity of PM_2.5 samples from Shenzhen and Taiyuan [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(6): 483-487.
[10]	LI Ying, CHEN Xiaming, LI Hanrong, LUO Te. Genotoxicity of three kinds of electric mosquito repellents on plant root tip cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(5): 401-405,411.
[11]	WEN Hairuo, GUO Yajuan, HUANG Zhiying, WANG Xue, DAN Mo. Induction of cytotoxicity and DNA damage by iron oxide nanoparticles with different surface modifications in A549 cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(6): 413-421.
[12]	XIA Ying, FU Shaohua, ZHANG Yinjing, WANG Wei. Genetic toxicity test of a pesticide, Paichongding [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(2): 136-139.
[13]	CAO Yiyi, XI Jing, TANG Weifeng, YOU Xinyue, LIU Weiying, LUAN Yang. Genotoxicity evaluation of triclosan in vitro [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(1): 71-75.
[14]	JIANG Yi, JIA Xiaohui, LI Peining, CHEN Xiujuan, LIU Donghong, LIU Xiangmei. Ames mutagenicity assay on five plastic surface chemicals in racetrack [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2017, 29(4): 309-312.
[15]	WANG Zhi, LING Xi, ZHANG Guowei, GAO Jianfang, ZOU Peng, JING Che, LIN Zhetao, LIU Jinyi, CAO Jia, AO Lin. Effect of folic acid on DNA demethylation and chromosomal damage in mice after their inhalation exposure to 1, 3-butadiene [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2017, 29(3): 189-193.

STUDY ON MUTAGENICITY OF THIFENSULFURON

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments