农药甲胺基阿维菌素苯甲酸盐的致突变性研究

doi:10.3969/j.issn.1004-616x.2006.01.021

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2006, Vol. 18 ›› Issue (1): 71-073.doi: 10.3969/j.issn.1004-616x.2006.01.021

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Study on Mutagenicity of Emamectin Benzoate

LIU Yong-xia;LI Mao-jin;LIU Yan-zhong;LI Yan;XIE Lin

Shandong Institute of Occupational Health,Jinan 250062,Shandong,China

Received:2005-01-29 Revised:2005-05-18 Online:2006-01-30 Published:2006-01-30
Contact: LIU Yong-xia

Abstract

Abstract: BACKGROUND ＆ AIM: To explore the potential mutagenicity of emamectin benzoate. MATERIAL AND METHODS: The potential mutagenicity of emamectin was examined with Ames test, micronucleus test of polychromatic erythrocytes in bone marrow and chromosomal aberration test of spermatocytes in mice. RESULTS: The number of revertant colonies was no more than twice that of spontaneous colonies for each dosage group. Compared with the control group, there was no significant difference in the ratio of micronucleus and the ratio of chromosomal aberration for each dosage group(P>0.05). CONCLUSION: No mutagenicity of emamectin benzoate was found.

Key words: emamectin benzoate, ames test, micronucleus, chromosomal aberration, mutagenicity

CLC Number:

LIU Yong-xia, LI Mao-jin, LIU Yan-zhong, LI Yan, XIE Lin. Study on Mutagenicity of Emamectin Benzoate[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2006, 18(1): 71-073.

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Study on Mutagenicity of Emamectin Benzoate

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