Abstract: OBJECTIVE: To investigate the use of Mammotome minimally invasive biopsy system and BI_RADS_US in the early diagnosis of breast carcer. METHODS: Clinical record of 97 tiny breast tumor(<1 cm) in our hospital from March 2008 to March 2009 were reviewed and analyzed. RESULTS: Using BI_RADS_US to predict histopathologic diagnosis of tiny breast tumor, sensitivity was 82.35％,specificity 97.5％, positive predictive value 87.5％,negative predictive value 96.30％,compliance rate 94.84％. The differences in bleeding, wound healing and scar size between mini_cut Mammotome group and open operation group in benign tiny breast tumor revealed statistical significance(P<0.05). CONCLUSION: BI_RADS_US could provide accurate histopathologic diagnosis of tiny breast tumor. Moreover,combining this with Mammotome minimally invasive biopsy system could cure tiny breast tumors.

Key words: Mammotome invasive biopsy system, ultrasound guided_Mammotome invasive biopsy system, breast cancer