Carcinogenesis, Teratogenesis & Mutagenesis ›› 2004, Vol. 16 ›› Issue (4): 244-246.doi: 10.3969/j.issn.1004-616x.2004.04.019

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Evaluation of Transposed Ovaries in Cervical Cancer Patients After Surgery and Pelvic Irradiation

LI Cong-zhu, ZHAI Yu-xia, HUANG-Ping, et al   

  1. Department of Gynecologic Oncology,Tumor Hospital of Shantou University Medical College,Shantou 515031, China
  • Received:2004-02-07 Revised:2004-05-20 Online:2004-07-30 Published:2004-07-30
  • Contact: LI Cong-zhu

Abstract: BACKGROUND & AIM: To evaluate the value of transposed ovaries in cervical cancer patients after surgery and pelvic irradiation. MATERIAL AND METHODS: In 75 patients with stage Ia2~IIb cervical cancer, 24~45 years of age, Wertheim-Meigs radical hysterectomy was performed with preservation of one or both ovaries transposed outside the pelvis. For evaluation of the post-treatment hormonal function of gonads, serum FSH, LH, estradiol and progesterone levels were assayed after irradiation. RESULTS: The method of transposed ovaries is safety and effective. No patients with retained ovaries developed metastatic disease. The patients who postoperative radiotherapy be indicated occur a substantial loss of ovarian function, but the levels of estradiol and progesterone significantly higher than in the radical therapy group. CONCLUSION: It is our opinion that normal ovaries can be preserved in the women under the age of 45 years at the time of radical hysterectomy for stage Ib~IIb cervical cancer.

Key words: cervical cancer, young patient, transposition of ovary