双酚A与肿瘤相关性的研究进展

doi:10.3969/j.issn.1004-616x.2020.06.015

摘要/Abstract

摘要： 双酚A（BPA）是一种常见的、具有显著类雌激素作用的环境内分泌干扰物，被认为与多种疾病的发生有关。恶性肿瘤作为严重影响人类健康的一类疾病，其与BPA的关联性受到了研究者的广泛关注并开展了深入的研究。本文总结了BPA与恶性肿瘤相关研究的最新进展，包括激素依赖性及非激素依赖性肿瘤，以及相应的流行病学研究或体内、外实验研究证据；同时，归纳了BPA促进恶性肿瘤发生发展的分子机制；此外，还分析了当前研究中存在的问题和不足。以上内容将为进一步研究BPA对恶性肿瘤发生发展的影响，为寻找预防或降低BPA健康损伤的措施提供有益信息。

关键词: 环境内分泌干扰物, 双酚A, 肿瘤, 分子机制

中图分类号:

R730.2

陈赵静, 王朦朦, 杨军, 吴茵茵. 双酚A与肿瘤相关性的研究进展[J]. 癌变·畸变·突变, 2020, 32(6): 485-489.

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