癌变·畸变·突变 ›› 2021, Vol. 33 ›› Issue (3): 161-162.doi: 10.3969/j.issn.1004-616x.2021.03.001

• 专家述评 •    下一篇

衰老和恶性肿瘤──防治的思考

程书钧   

  1. 中国医学科学院北京协和医学院肿瘤医院, 北京 100021
  • 收稿日期:2021-04-20 修回日期:2021-04-22 出版日期:2021-05-30 发布日期:2021-06-09
  • 作者简介:程书钧(1939-),男,中国工程院院士,国家“恶性肿瘤发生与发展的基础研究”项目(973计划)首席科学家。曾任中国医学科学院肿瘤研究所副所长、肿瘤医院副院长、中国环境诱变剂学会理事长、中国抗癌协会副理事长、中华医学会理事。现任《癌变·畸变·突变》杂志主编。Tel:010-67766703;E-mail:chengshj@cae.cn

Aging and malignant tumor─Thought on prevention and control

CHENG Shujun   

  1. Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  • Received:2021-04-20 Revised:2021-04-22 Online:2021-05-30 Published:2021-06-09

摘要: 恶性肿瘤是一种和人衰老过程密切相关的整体性的疾病,是衰老过程中细胞损伤及人体宿主修复能力动态平衡失调的结果。宿主因素在恶性肿瘤的发生、发展中起重要作用。不能只单纯治疗人的肿瘤,更要重视治疗带有肿瘤的病人。增强患者自身的抗病自愈能力,实现癌症病人长期“带瘤生存”是未来肿瘤研究的重要方向。延缓衰老可以有效推迟恶性肿瘤的发生,降低恶性肿瘤的死亡率。

关键词: 衰老, 恶性肿瘤, 带瘤生存, 肿瘤防治

Abstract: Malignant tumor is a kind of integral disease which is closely related to human aging process. Tumor is the result of dynamic balance disorders between cell damage and human host's ability to repair during aging. Host factors play an important role in the occurrence and development of malignant tumor. We should not only treat human tumors, but also treat the patients with tumors. We should enhance the patient's ability of disease resistance and self-healing. To realize the long-term survival of cancer patients with tumor is an important direction of future cancer research. Delaying aging and preventing malignant tumor have much in common. Anti-aging can effectively delay the occurrence of malignant tumors and reduce their mortality.

Key words: ageing, malignant tumor, survival with tumor, cancer prevention and control

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