赤包根茎醇提取物致突变性研究

doi:10.3969/j.issn.1004-616x.1998.03.013

Carcinogenesis, Teratogenesis & Mutagenesis ›› 1998, Vol. 10 ›› Issue (3): 173-175.doi: 10.3969/j.issn.1004-616x.1998.03.013

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A STUDY ON THE MUTAGENICITY OF ETHANOL EXTRACT OF THLADIANTHA DUBIA BUNGERHIZOME

Wu Boyan , et al

Biological Dept . of HeiL ongjiang University of Chinese Medicine , Harbin 150040

Received:1900-01-01 Revised:1900-01-01 Online:1998-05-30 Published:1998-05-30

Abstract

Abstract: We studied the mutation indnad by ethanol ext ract of Thladiatha dubia bunge rhizome in the bone marrow cell of mice and towards the TA98 and TA100 bactarial lines by methods of PCE2MNT and CAT of mice and Ames test . The result s indicated that 30 % and 50 % ethanol ext ract of thladiantha dubia bunge rhizome did not induce significantly increase of PCEMNF and CAP in mice. The mutagenicity of ethanol ext ract also showed negative result in Ames best . All result s indicated that ethanol ext ract of thladiantha dubia bunge rhizome is not damage effect to genetic material.

Key words: Ethanol ext ract of Thladiatha dubia bunge rhizome, Micronucleus, Chromosome aberration, Ames test, Mutagenicity.

Wu Boyan , et al. A STUDY ON THE MUTAGENICITY OF ETHANOL EXTRACT OF THLADIANTHA DUBIA BUNGERHIZOME[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 1998, 10(3): 173-175.

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A STUDY ON THE MUTAGENICITY OF ETHANOL EXTRACT OF THLADIANTHA DUBIA BUNGERHIZOME

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