Carcinogenesis, Teratogenesis & Mutagenesis ›› 1999, Vol. 11 ›› Issue (2): 99-101.doi: 10.3969/j.issn.1004-616x.1999.02.012

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THE EFFECTS OF MINERAL WATER WITH HIGH RADIATION ON MICRONUCLEUS AND SPERMATOZOON OF MICE

Lu Wenge1 , Ba Yue1 , Chen Xuemin1 , Yang Jianxun1 , Fu Runfang2 , Feng Guoqing2 , Wang Xilin1 , Gao Jinshe1   

  1. 1 Department of Envi ronmental Heal th , Henan Medical University , Zhengz hou  450052  2 Department of Pharmacology , Henan Medical University , Zhengz hou  450052
  • Received:1998-03-24 Revised:1998-06-07 Online:1999-03-30 Published:1999-03-30

Abstract: Mineral water with high radiation was tested to evaluate it s genetic toxicity. In the experiment the Kunming mice were randomly divided into 3 groups , one group , fed with tap water and the other two with different highly2radiated mineral water. Samples were collected on the 50th day ,100th day ,150th day , respectively. Result s showed that the f requencies of the micronucleus and number of motile sperms of the mice drinking highly-radiated mineral water are significantly different ( P < 0. 05) as compared with those drinking tap water at certain period of time. Thus it suggested that the mineral water with high radiation might possess potential mutagenic effect on the animals.

Key words: High radiation mineral water, micronucleus, Spermatozoon