Carcinogenesis, Teratogenesis & Mutagenesis ›› 2000, Vol. 12 ›› Issue (1): 18-022.doi: 10.3969/j.issn.1004-616x.2000.01.006

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STUDY ON MONITORING GENOTOXICANT POLLUTION IN SURFACE WATER OF YANGZHONG CITY USING MICRONUCLEUS TEST AND COMET ASSAY

ZHONG Yuan1 , FENG Shao-long1,SU Qing1 , XIE Chao-yun1 , LUO Yu1 , KONG Zhi-ming1 , WAN Hen-qing2   

  1. 11 State Key Laboratory of Pollution Control and Resource Reuse, Department of Environmental Science and Engineering, Nanjing University, Nanjing 210093, China; 21 Yangzong County Envi ronmental Protection Part, Yangzong 212200, China
  • Received:1999-05-26 Revised:1999-09-12 Online:2000-01-30 Published:2000-01-30

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Abstract: Purpose and Methods : In this study , the micronucleus test and comet assay of V ice f aber were used to screen pollution situation of the surface water of Yangzhong city. Results : The result s showed that the water of Yangzi river and Hongxin river was heavily polluted (Pollution Index > 3) and pollution of other water body was slight . Using the comet assay to detect the DNA damage induced by the organic ext ract s f rom four water samples , the result s indicated that both the comet assay and the micronucleus test were able to detect the geno2 toxic potential of different water body and the comet assay seemed to be more sensitive than micronucleus test . Conclusion : Combination of the comet assay and the micronucleus test might therefore be recommended for monitoring the genotoxicant pollution of water body.

Key words: Yangzhong city, surface water, micronucleus test of V ice faber, comet assay

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