Abstract: Purpose and Methods : Induction of micronuclei and nuclear anomalies in the peripheral blood erythrocytes and the kidney leucocytes of Monopterus albus by the herbicide J ing Ke Cao Xing was studied. Results :The result s showed that the herbicide can increase the f requencies of micronuclei and nuclear anomalies in the two kinds of cells. At certain concent ration and time , the f requencies of damage items were significantly different in comparison with cont rol groups. But , at other concent ration and time , the differences were insignificant . Conclusion : All the result s suggested that the herbicide can cause significant genetic damages to the erythrocytes and the leucocytes of Monopterus albus at certain concent ration and time.

Key words: Monopterus albus, J ing Ke Cao Xing, erythrocyte, leucocyte, micronucleus, nuclear anomalies