Carcinogenesis, Teratogenesis & Mutagenesis ›› 2001, Vol. 13 ›› Issue (2): 98-101.doi: 10.3969/j.issn.1004-616x.2001.02.010

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THE MUTAGENICITY STUDY OF CHLORINEDIOXIDE USINGMICRONUCLEUS TEST IN VICIA FABA ROOT TIP CELLS

JNG Hui-quan, NI Xiao-ping, KOU Yu   

  1. Center of Disease Prevention and Control in Hangzhou, Hangzhou 310006, China
  • Received:2000-08-28 Revised:2000-11-16 Online:2001-04-30 Published:2001-04-30

Abstract: Purpose and Methods : The mutagenecity of two batches of chlorine dioxide (ClO2) were studide using-micronucleus test in V icia f aba root tip cells. Results : The f requencies of micronucleus of two kinds of ClO2 were (17. 91 ±4. 80) ‰ and (17. 5 ±3. 12) ‰ respectively when the diluent multiple of ClO2 was at 1 : 100.=Comparing with the tap water group , the differences (χ2A = 30. 57 , χ2B-= 29. 60 P < 0. 01) was statistically significant and the dose2effect relationship ws clear. Conclusion : Clorine dioxide has mutagenicity. We should pay attention to safety of it s apllication in food and water.

Key words: Pollution of Sushui River, Wells along the river, Genotoxicity, Micronucleis test.

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