Carcinogenesis, Teratogenesis & Mutagenesis ›› 1998, Vol. 10 ›› Issue (1): 8-011.doi: 10.3969/j.issn.1004-616x.1998.01.004

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A FELLOW2UP STUDY ON MICRONUCLEI OF PERIPHERAL BLOOD LYMPHOCYTE IN PERSONS EXPOSED TO 137CS RADIATION ACCIDENT

Bai Yushu1 ,Cao J iazhen2 , Huang Qilong1 , Zhang Xiuxia1 , Guan Shurong1 , Chai Wen1 , Xu Mi2 anwen3 , Li J ingjun3 , Wang Hua2 , Duan Ruping4   

  1. 1L aboratory of Indust rial Hygiene , Minist ry of Heal th , Beijing 100088 1L aboratory of Indust rial Hygiene , Minist ry of Heal th , Beijing 100088 2Heilongjiang Province Hygiene and Epidemic S tation , 3 Haerbin Medical University 4Mudanjiang City Instit ute of Occupational Disease
  • Received:1900-01-01 Revised:1900-01-01 Online:1998-01-30 Published:1998-01-30

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Abstract: This paper resport s micronuclei of peripheral blood lymphocyte of 39 cases exposed to 137　Csγ2ray in a period of 5 months. The accumulated equivalent doses were 5～2105mSv. The result s show that micronucleus f requencies in the both groups of exposed and cont rol were very near . The difference was not significant . At that time , micronucleus f requencies using method of routine culture in exposed group were higher that those in the cont rol one , and they had correlated relationship with accumulated doses. At 5th year after irradiation , micronuclei were examined by cytokinesis2block micronucleus method. The result s show that the f requencies of micronucleus in exposed group were higher than those in the cont rol. The difference was very significant . It indicated that CB method increased precision and reliability for micronucleus assay.

Key words: 137　Cs, accidental radiation, micronucleus, cytochalasin2B, follow2up