Carcinogenesis, Teratogenesis & Mutagenesis ›› 2000, Vol. 12 ›› Issue (2): 115-116.doi: 10.3969/j.issn.1004-616x.2000.02.018

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THE STUDY ON THE ANTAGONISM OF VITAMIN C( VC) ON MUTAGENICITY INDUCED BY CHROMIUM.

LI Ding , LIANG Gang , WEI Ya-bing   

  1. Shenyang Sanitary and Anti-epidemic Station , Shenyang  110031 , China
  • Received:1999-08-09 Revised:1999-11-30 Online:2000-04-30 Published:2000-04-30

Abstract: Purpose and Methods : Using the micronucleus test in vivo , the effect s of Vitamin C on the mutagenicity induced by chromium were studied. Results : the Vitamine C had obvious antimutagenic potentials at the concent ration of 2. 5 % and 5. 0 %( P < 0. 05) , and showed the dose2effect relationship. Conclusion : results indicated that Vc could antagonize the matagenicity induced by chromium.

Key words: micronucleus, Vitamine C, antimutagenic effect

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